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8. Nobel Prize in Medicine (1977) awarded to Rosalind Yalow for: invention of the radioimmunoassay (RIA).

href="http://www.pnas.org/content/109/3/669.full">Rejection: For href="http://www.pnas.org/content/109/3/669.full">Rejection: "For  years after winning the Nobel Prize, Yalow proudly showed this rejection letter in her public presentations.
 presentations."