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In this paper we present the first model of Neanderthals potential distribution across Europe during the Last Interglacial (Eemian, MIS 5e, ~130 ka BP). We have applied a robust state-of-the-art modeling approach to take advantage of a sparse set of archaeological records and a palaeoclimatic simulation to produce the model. We analyzed the model using regression-tree based statistical methods to assess how environmental variables shaped habitat suitability at continental and local scales, and assessed to what extent our preliminary hypothesis on the abiotic drivers of Neanderthals distribution matched the results of the model.  The discussion about the distribution of Neanderthals across Europe during the Eemian has been the focus of just a few papers during the last years \cite{Richter2006, \cite{Richter2005, Richter2006,  Wenzel_2007, Gaudzinski2011}. \cite{Krause_2007} neanderthals in asia and siberia \cite{Beeton_2013}