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Taylor Dunn edited untitled.tex
over 8 years ago
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$\Gamma_b \equiv $ ruffle recruitment rate per bacterial density, per ruffle
\noindent Once attached, a bacterium can cause
ruffling ruffling, invade the host cell and stay vacuolar, or invade the host
cell. cell and escape into the cytosol.
$\Gamma_r \equiv $ ruffle formation rate per attached bacteria, per host cell
$\Gamma_v \equiv $
vacuolar invasion rate
via SCV per attached bacteria, per host cell
\noindent And finally, once internalized, a bacterium may escape the vacuole and enter the cytosol. $\Gamma_c \equiv $
escape cytosolic invasion rate per
vacuolar bacteria attached bacteria, per host cell
\noindent There is evidence that suggests a physical limit to the number of ruffles per cell $\tilde{r}_{\rm max}$, and the number of invaded bacteria per cell $\tilde{b}_{x, \rm max}$, so we define the following effective rates.