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- Missing data are left as empty cells.  - No comments are allowed in the Data and Metadata worksheets but other worksheets can be added for this purpose.  The Data worksheet:
The Metadata worksheet:
Notes:  1. Currently, pandas does not yet support the reading and the writing of ODS (Open Document Spreadsheets) but there are many requests for this feature and it should be feasible soon ([pandas/issue 2311](https://github.com/pydata/pandas/issues/2311)).