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Charith Bhagya Karunarathna edited section_Methods_subsection_Data_simulation__.tex
over 7 years ago
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\end{itemize}
\item Logistic regression model of disease status.
\begin{itemize}
\item
Assign Once haplotypes were paired into 1500 individuals, disease status
was assigned to the
1500 individuals based on randomly sampled risk SNVs from the middle
part of the genomic region
$(950kbp - 1050kbp)$ and a diploid model of
disease risk. $950kbp−1050kbp$.
\item For risk SNVs, the number of copies of the derived allele increases disease risk according to a logistic regression model,
$$
{logit}\{P(D=1|G)\} = {logit}(0.2)+ \sum_{j=1}^{m} 2 \times G_j,\;\;\mbox{where,}