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\item Success in localization was declared if the strongest signal was in the risk region.  \end{itemize}   \end{itemize}  \item Paragraph to discuss how we will score scored  localization and signal detection  for each of these methods. \begin{itemize}  \item localization: Localization:  scoring the distance of the peak signal from the risk region based on the average distance across the entire genomic region. \item Detection: max. statistics across all the SNV as our global test statistics and determined its null distribution by permuting the case-control labels.  \end{itemize}  \end{enumerate}