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\begin{itemize}  \item CAVIARBF \cite{Chen_2015} is a fine-mapping method that uses marginal test statistics for the SNVs and their pairwise association to approximate the Bayesian multivariate regression of phenotypes onto variants that is implemented in BIMBAM \cite{Servin_2007}. However, CAVIARBF is much faster than BIMBAM because it computes Bayes factors using only the SNVs in each causal model. These Bayes factors can be used to calculate the posterior probability of SNVs being causal in the region (the posterior inclusion probability).  \begin{itemize}  \item To compute the probability of SNVs being causal, set of models and their Bayes factors have to be considered. Let $p$ be the total number of SNVs in a candidate region, then the all possible number of causal models is $2^p$. To reduce the number of causal models to evaluate and save computational time and effort, CAVIARBF imposes a limit, $L$, on the number of causal variants. So, this limitation reduces the number of models to evaluate in the model space from $2^p$ to $ \sum_{i=0}^{L} \dbinom{p}{i} $, where $L$ is the number of causal SNVs in the model. Since there are were  2747 SNVs in our data, example dataset,  to keep the computational load down, we considered $L=2$. $L=2$ throughout this investigation..    \end{itemize}  \item Elastic-net \cite{Zou_2005}: A hybrid regularization and variable selection method that linearly combines the L1 and L2 regularization penalties of the Lasso \cite{Tibshirani_2011} and Ridge \cite{Cessie_1992} methods in multivariate regression. WE CONSIDER ONLY MAIN EFFECTS FOR SNVs IN OUR ELASTIC NET MODELS.