Charith Bhagya Karunarathna edited subsection_Analysis_and_Approaches_begin__.tex  over 7 years ago

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\item Each of the variant site in the case-control sample is tested for an association with the disease outcome.  %\item Recommended when the cell counts are small, as is expected for rare variants.  \end{itemize}  \item Single-variant tests are less powerful for rare variants \cite{Asimit_2010}. We therefore considered three classes of analysis: pooled-variant methods, modelling joint-modelling  and tree-based methods. \end{itemize}   \item Pooled-variant method  \begin{itemize}