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\end{itemize}  \item Logistic regression model of disease status.  \begin{itemize}  \item Assign disease status to the 1500 individuals based on randomly sampled risk SNVs from the mid region (950kbp $(950kbp  - 1050kbp) 1050kbp)$  and a diploid model of disease risk. \item For risk SNVs, the number of copies of the derived allele increases disease risk according to a logistic regression model,  $$  {logit}\{P(D=1|G)\} = {logit}(0.2)+ \sum_{j=1}^{m} 2 \times G_j,\;\;\mbox{where,}