Charith Bhagya Karunarathna edited subsection_Several_popular_methods_begin__.tex  over 7 years ago

Commit id: 0120410ed2ca06c3eb23760bea350ae522af7caf

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\end{itemize}  \end{itemize}  \end{itemize}  \end{enumerate}  \item Tree-Based method  \begin{itemize}  \item Reconstructed genealogical trees at each SNV (Blossoc, \citeNP{Mailund_2006}): A fast method to localize the disease-causing variants. 

\item Localization: scoring the distance of the peak signal from the risk region based on the average distance across the entire genomic region.   \item Detection: For a given simulated dataset and a given method, we used max. statistics across all the SNV as our global test statistics and determined its null distribution by permuting the case-control labels.   \end{itemize}  \end{enumerate}