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Charith Bhagya Karunarathna edited subsection_Several_popular_methods_begin__.tex
over 7 years ago
Commit id: 0120410ed2ca06c3eb23760bea350ae522af7caf
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\end{itemize}
\end{itemize}
\end{itemize}
\end{enumerate}
\item Tree-Based method
\begin{itemize}
\item Reconstructed genealogical trees at each SNV (Blossoc, \citeNP{Mailund_2006}): A fast method to localize the disease-causing variants.
...
\item Localization: scoring the distance of the peak signal from the risk region based on the average distance across the entire genomic region.
\item Detection: For a given simulated dataset and a given method, we used max. statistics across all the SNV as our global test statistics and determined its null distribution by permuting the case-control labels.
\end{itemize}
\end{enumerate}