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\section{Impact}  \label{}   Indicate in what way new research questions can be pursued as a result of the software (if any).  Indicate in what way, and to what extent, the pursuit of existing research questions is improved (if so).  Indicate in what way the software has changed the daily practice of its users (if so).  Indicate how widespread the use of the software is within and outside the intended user group.  Indicate in what way the software is used in commercial settings and/or how it led to the creation of spin-off companies (if so).