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Thanks to all the reviewers for your helpful comments!  The major weaknesses of this manuscript that I've addressed are: \begin{enumerate}  \item I gave the impression that one needs to scan human calibration phantoms at each site to properly power a multisite study with nonstandardized parameters, which is very costly and certainly was not our intention! I have focused on emphasizing the statistical model which takes MRI bias into account (that bias was measured via calibration, but that is not the central point).