deletions | additions       diff --git a/Caramanos_2010_looked_specifically_at__.tex b/Caramanos_2010_looked_specifically_at__.tex  index 557eb42..570d6d7 100644  --- a/Caramanos_2010_looked_specifically_at__.tex  +++ b/Caramanos_2010_looked_specifically_at__.tex 
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Caramanos 2010 looked specifically at repositioning in relation to SIENA, which is a longitudinal analysis, but one could assume that repositioning affected the scan-rescan variability of some ROIs in our cross-sectional analysis. We have assumed that the consistency of positioning varies between sites, because a standardized positioning protocol was not defined. A big reason for this was to be able to incorporate data that was previously acquired for future studies. We have some measure of positioning consistency that was reflected in the amount of variability due to the site-by-run interaction term in our ICC calculation, since variability in positioning would contribute to the variability of volumes between runs at particular sites. This variance component was much smaller than the variance due to subjects/sites/subjects x site/unexplained, and the specific variance component for runxsite run x site  was reported for each ROI in the supplemental materials. Overall, the majority of the variance was explained by subject, site, and the subjectxsite subject x site  interaction than by the site by run term.