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**Results and Discussion**  The vast majority of the bacteria (45/48) behaved very similarly in space and on earth (Table 1, Figure X). Only three bacteria showed a significant difference in the two conditions; _Bacillus safensis_, _Bacillus methylotrophicus_, and _Microbacterium oleivorans_. However, upon Sanger sequencing the 16S rRNA gene from all cultures obtain from  the wells on the space plates and the ground plates, we observed contamination of the _B. methylotrophicus_ and _M. oleivorans_ wells and therefore discarded those data. The remaining candidate was _Bacillus safensis_, collected at the Jet Propulsion Laboratory (JPL-NASA) on a Mars Exploration Rover before launch in 2004. As part of standard Planetary Protection protocols, all surface-bound spacecraft are sampled during the assembly process and those strains are then saved for further analysis. We obtained this strain as part of a collection of JPL-NASA strains to send to the ISS (Table 1). In this experiment, _Bacillus safensis_ grew to a final density of ~60% higher in space than on the ground, with very little variation between replicates (Figure X). The genome sequence of this strain, _Bacillus safensis_ JPL-MERTA-8-2 has just been published \cite{26586895} and may contain clues as to why this strain behaved so differently in space.