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\section{Introduction}
Chagas Chagas' disease is a
global tropical parasitic
disease mostly epidemic
of global reach, spread mostly across Latin America.
WHO \ref{http://www.who.int/mediacentre/factsheets/fs340/en/} estimate The World Health Organization (WHO \ref{http://www.who.int/mediacentre/factsheets/fs340/en/}) estimates more than six million infected people worldwide. Most transmissions
occurs occur in the Americas via the \textit{Trypanosoma cruzi} parasite, vector-borne by the \textit{Triatomine} insect family. Other relevant routes of transmission include blood transfusion and congenital transmission,
estimating with an estimated 1300 newborns infected each year \ref{trabajos_de_}.\begin{comment} en el drive estan las ppt del min salud \end{comment}.
Enduring chronically in the infected individual,
Chagas Chagas' disease can last years without being detected. This in turn reduces the chance of effective treatment and
the tracking of infected individuals.
The spatial Spatial dissemination of a congenitally transmitted disease
offsets sidesteps the available measures to
control monitor risk
groups and groups, slowly
introduce introducing the
disease to infection in the general population. Long-term human mobility plays a key role in this process.
In
Argentina Argentina, vector control
campaigns campaings have been
ongoing the main epidemic counter-measure for more than thirty
years as the main epidemic counter-measure. years. The \textit{Gran Chaco}, situated in the northern part of the
country country, is home to most of the infected triatomines. The ecoregion's
poor socio-demographic conditions
aids further supports the parasite's lifecycle.
Domestic human, Human, bug and animal
domestic interactions
preserve foster the continuous
development appearance of new infection cases,
specially in particularly among the
poorer poorest.
The dynamic interaction of the triatomine infested areas
and the with human mobility patterns present a difficult scenario to track down individuals or spots with high prevalence of infected people or
high transmission risk. Available methods of surveying the state of
the Chagas Chagas' disease in Argentina nowadays are limited to individual screenings of individuals.
To the best of our knowledge the work described here is the first attempt to use Here, we aim at using mobile phone data
in order to understand Chagas' epidemic spatial structure.
\begin{comment} Existe una forma de decir esto de manera correcta.. o asi les parece bien? \end{comment}
Recent national estimates indicate that there exist at least one million people carrying the
parasite parasite, with more than seven million exposed. Experts \begin{comment} aca como referencio a Diego Weinberg y Mundo Sano? \end{comment} underline the current difficulties faced by the national health
systems systems, where on
average, average only two thousand people are treated yearly for
Chagas Chagas' disease. \begin{comment} aca nuevamente esta referencia es de MS \end{comment}.
There exist different approaches in the literature
making that use
of mobile
phone data
applied to study epidemiological or health problems. \begin{comment} La siguiente info la saco de aqui https://docs.google.com/document/d/1ZClgYFTLCxmg7wvRXqz2V1EP7Wcg0vd2ZwEBOLW2VOk \end{comment} Amy Wesolowski et al \ref{Wesolowski} quantify the impact of human mobility on Malaria disease movement in Kenya
with through disease prevalence information; Tizzoni et al \ref{Tizzoni} compare theoretical mobility models, models studied with
CDRs Call Detail Records (CDRs), and mobility census data to infer
Other works directly work on CDRs to characterize human mobility. Inferences patterns of daily flow
\footnote{A complete survey of mobile traffic analysis articles may be found in Fiore, Naboulsi, Ribot & Stanica's work \ref{mobile_survey} }are explored in sarraut
...
su edad y género, etc.
Here we explore the use CDRs to predict population movements between the \textit{Gran Chaco} ecoregion to the rest of the
country. country, thus providing a proxy for the epidemic spread. Data is timestamped and geolocalizated by the position of the antenna used to place the call. Privacy is
also ensured by identifying users by their hashed ID. \begin{comment}el tema de la privacidad es siempre tan importante que lo pongo aca... haria falta agregar que no tenemos acceso a las claves de encriptacion. \end{comment}
Public health policy and epidemiological interventions could greatly benefit from the study of long-term national mobility patterns. Characterization of human movements to and from the ecoregion is key to the problem of targetting infected individuals at a national scale. To the best of our knowledge, data on the subject is vastly lacking, inexistent or hardly accesible to researchers.
