To determine if OS cockroach survival was proportional to the number of bacteria present in the infection inoculum, serial dilutions of F. tularensis LVS were injected into into the hemocoel of juvenile cockroaches that weighted between 0.7 and 1.0 grams. Following infection, cockroaches were housed at 37\(^{\circ}\)C and survival was monitored over the course of 7 days. Overall, the percentage of cockroaches in each group that survived infection and the rates of death were dose-dependent. None of the cockroaches inoculated with 10^5 or 10^6 CFU of F. tularensis LVS survived beyond day 4 (Figure 2). In comparison, 5 out of 8 cockroaches infected with 10^4 CFU of F. tularensis LVS survived through day seven post-infection (p=0.0141; compared to 10^5 CFU group) and 7 out of 8 cockroaches infected with 10^3 CFU of F. tularensis LVS survived through day seven post-infection (p<0.001; compared to 10^5 CFU group). Injection of PBS alone did not result in any cockroach deaths.