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\textbf{Figure 7. Rescue of OS cockroaches with antibiotics after lethal dose of \textit{F. tularensis LVS}.}  Groups of OS cockroaches (n=???) were infected with 3.4 x 10^6 CFU \textit{F. tularensis} LVS and treated with either  vehicle controls (A) (A; oral sucrose or injected PBS)  or the indicated antibiotics (B-F) at 2, 48, and 96 hours post-injection. Solid blue lines indicate groups treated with oral antibiotics. Dashed black lines indicate groups treated by systemic injection. (A) Control Statistical differences between  groupsthat were either injected with PBS or fed a sucrose solution without antibiotics all died within 7 days of infection. Streptomycin (B) and gentamicin (C) only  were protective when delivered systemically (p=0.00199 and p<0.001, respectively), but not when delivered orally. There is no statistical difference between route of antibiotic delivery for doxycycline (E) and ciprofloxacin (F). Resazurin (D), a dye that has been shown to have anti-\textit{Francisella} properties \textit{in vitro}, failed to prevent cockroach death determined  byeither route.  Kaplan-Meiersurvival curves were compared by  log-rank analysis.