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\section{Results}  \subsection{Challenge \subsection{Infection  of \textit{B. dubia} with \textit{F. tularensis} LVS} To determine if OS cockroach survival was proportional to the number of bacteria present in the infection inoculum, serial dilutions of \textit{F. tularensis} LVS were injected into into the hemocoel of juvenile cockroaches that measured greater than 1.5 cm in length. Infected cockroaches were housed at 37$^{\circ}$C and survival was monitored for 7 days. The percentage of each group that survived infection and the rate of death were dose-dependent; no OS cockroaches survived infection with 10^{5} CFU of \textit{F. tularensis} LVS and all cockroaches died by day five post-challenge; post-infection;  60 percent of cockroaches infected with 10^{4} CFU of \textit{F. tularensis} LVS survived through day seven post-challenge; post-infection;  and 90 percent of cockroaches infected with 10^{3} CFU of \textit{F. tularensis} LVS survived through day sevenpost-challenge  (Figure 2). Injection of PBS alone did not result in any deaths.