Nathan edited figures/Fig_Abx/caption.tex  over 8 years ago

Commit id: 03ef149f05a007fb8d394a5adc573f145a5d0d33

deletions | additions      

       

\textbf{Figure 7. \textbf{Table 2.  Rescue of OS cockroaches with antibiotics after lethal dose of \textit{F. tularensis LVS}.} Groups of OS cockroaches (n=10) (n=8-18)  were infected with between 1.3 x 10^6 and  3.4 x 10^6 CFU \textit{F. tularensis} LVS and treated with either vehicle controls (A; oral sucrose or injected PBS) (approx. 100 LD_{50}s) followed by intrahemocoel injection (i.h.)  or peroral feeding (p.o.) of a solution containing  theindicated  antibiotics (B-F) indicated  at 2, 48, and 96 hours post-injection.Solid blue lines indicate groups treated with oral antibiotics. Dashed black lines indicate groups treated by systemic injection.  Statistical differences between groups were determined by log-rank (Mantel-Cox) analysis. analysis using the 'survival' package in the R programming environment (version 3.2.1).  Asterisks indicate significant differences compared to the corresponding vehicle  control(no antibiotic)  group (*=p<0.05, ***=p<0.001). Pound symbols indicate significant differences between oral and systemic delivery or alternative routes  of the same antibiotic (##=p<0.01, ###=p<0.001). delivery (**=p<0.01, ***=p<0.001).