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\caption{Estimates of incidence derived from prevalence survey results, based on two estimation methods.}   \end{table}  It is not clear which method will perform better, validation would require a measurement of incidence. The second method requires a sufficient number of cases on treatment at the time of the survey (as a rule of thumb, at least 30 cases) tobe  generate stable estimates. When the number of cases on treatment is too small, the amount of propagated uncertainty renders estimates of incidence unusable and only the first approach is used. If both methods can be applied, results from two methods may be combined in a statistical ensemble approach as follows: