Jenna M. Lang edited Conclusion_With_continued_interest_in__.md  over 8 years ago

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#Conclusion  As outlined in the 2010 U.S. National Space Policy and in the bipartisan NASA Authorization Act of 2010, NASA is targeting the 2030s for a manned spaceflight to Mars, with one ultimate goal of having people live and work on the Martian surface (see www.nasa.gov/exploration and www.nasa.gov/mars). We know that the microbial communities found in our terrestrial built environments play an important role in human health. Therefore it’s crucial to characterize and understand the microbial population of the only environment in which people are currently living and working in space. This study is one small step in that direction.   This is the first time that the ISS has been analyzed in the broader context of the "microbiology of the built environment, and is the most in-depth comparison of the microbial communities found on the ISS to those found either in buildings or in the human microbiome. Perhaps surprisingly, given the extreme rarity of exchange with any external microbes, we find the ISS is species-rich, and is more similar to the surfaces of human homes on Earth than it is to human bodies. We found that the ISS is home to at least 12,554 distinct microbial species, including archea in very low abundance. The proportion Finally, it was found that, although there are significant differences in microbial communities associated with the ISS, Earth homes, and the human microbiome, those associated with the ISS and Earth homes are most similar. MAKE SOME STATEMENT ABOUT HUMANS IN SPACE INTERACTING WITH MICROBES AND HOW ITS NOT ACTUALLY THAT DIFFERENT THAN HERE ON EARTH??? No clue.. Needs some concluding statement.  With continued interest in space exploration, human presence in space via self-contained, built environments is increasing both in frequency and duration. Therefore it’s crucial to characterize and understand the microbial population of the environment in which people work and live in space. 12,554 distinct microbial species were identified, including archea in very low abundance. The Shannon diversity of the microbial community of the ISS is relatively high. There were no differences in microbe populations based on sampling locations. Additionally, ISS samples are similar in both phylogenetic diversity and the proportion of OTUs closely related to known human pathogens to the mechanically ventilated rooms of the health-care facilities. Finally, it was found that, although there are significant differences in microbial communities associated with the ISS, Earth homes, and the human microbiome, those associated with the ISS and Earth homes are most similar. MAKE SOME STATEMENT ABOUT HUMANS IN SPACE INTERACTING WITH MICROBES AND HOW ITS NOT ACTUALLY THAT DIFFERENT THAN HERE ON EARTH??? No clue.. Needs some concluding statement.