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#Abstract  ## Background   Project MERCCURI is (was?) a collaborative effort of UC Davis (microBEnet), Science Cheerleader, NanoRacks, Space Florida, and Scistarter.com. There are (were?) three aims for Project MERCCURI Aim 1 involves swabbing surfaces from sporting venues and other high-profile built-environment locations. This component includes a concurrent outreach effort in which 2000 "Citizen Scientists" are asked to contribute swabs of their cell phones and shoes. Aim 2 is a bacterial growth assay, in which non-pathogenic microbes collected from the surfaces in Aim 1, "compete" against each other, both on the surface of the Earth (at UC Davis) and onboard the International Space Station (ISS). Aim 3, the results of which are presented here, involves swabbing of 15 surfaces onboard the ISS to collect microbes for DNA-sequenced-based identification.  ## Methodology/Principal Findings  Sterile swabs were used to sample 15 surfaces onboard the International Space Station. The sites sampled were designed to be analogous to samples collected for 1) the Wildlife of Our Homes project and 2) the cell phone and shoe samples that were concurrently being collected for another component of Project MERCCURI.  ## Conclusions/Significance