David Coil edited Introduction.md  over 9 years ago

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The sequencing and _de novo_ assembly of genomes has already yielded enormous scientific insight revolutionizing a wide range of fields, from epidemiology to ecology. Our hope is that this workflow will help make this revolution more accessible to all scientists, as well as present educational opportunities for undergraduate researchers and classes.    There are several excellent resources that focus on smaller portions of this entire process, usually assembly and/or annotation. Examples include the Computational Genomics Pipeline \cite{Kislyuk_2010} and a "Beginner’s guide to comparative bacterial genome analysis" \cite{Edwards_2013} both of which start with data on the sequences of individual small fragments from an organism's genome (each DNA sequence generated by a sequencing system is known as a "read"). Another recent resource describing a roughly similar pipeline is focused on human mitrochondrial genomes\cite{Clarke_2014}. genomes \cite{Clarke_2014}.