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The selection of the protein domain families are based on two main criteria :  \begin{itemize}  \item a statistical relevant sequences sequence  sample of the protein family, the number of effective belonging sequences (similarity <0.8) greater than 500. \item presence at least of one experimental solved structure by X-ray diffraction of a biological assembly with homo-oligomers (containing the domain) with a good resolution (< 3A \AN)   \end{itemize} 
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