this is for holding javascript data
Guido Uguzzoni edited untitled.tex
almost 9 years ago
Commit id: 5c56aceb0169890d5abde1be4c65239e28fac176
deletions | additions
diff --git a/untitled.tex b/untitled.tex
index 5eed3a5..af5d1e1 100644
--- a/untitled.tex
+++ b/untitled.tex
...
Since the quaternary structure signals are likely to depends on the chains domains architecture, in order to be sure to include all the different biological assemblies that are experimentally at disposal we compare the DCA co-evolutionary signal with several PDB structures.\\
On this point some remarks are necessary. For each pfam domain selected:
\begin{itemize}
\item We collect all PDB with a biological assembly that
contains contain homo-oligomers of the pfam domain selected.
\item For each PDB we take into account repetition of the domain inside the same chain and different biological assemblies annotated. At the end one homo-oligomer pairing are identified unambiguously by pfam ID, PDB ID, chain identifier 1, chain identifier 2, chain 1 domain number,chain 2 domain number, biological assembly identifier.
\item We create a map between the alignment positions and the 3D inter-residues distances for each PDB ( \textbf{backmapping} ) To do so we extract the minimal distances between the heavy atoms between residues in the domain:
\begin{enumerate}
...