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Guido Uguzzoni edited section_Preliminary_Results_We_select__.tex
over 8 years ago
Commit id: 2d3ec8bf94db75e45dda0fcae2951790119c5fe0
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Moreover the diversity in the architectures present within the domain families and the variety of possible inter-chain binding affect the magnitude between intra and inter domain co-evolutionary signals.
We can select the intra-chain false positive more reliable looking at the value of the DCA score. This is more significative than the absolute ranking of the couples when comparing different pfam.
In figure 8,9 are summarize the results of this analysis. Selecting the couples of residues based on the DCA scores the prediction rate are higher up to
$80\%$, on $80\%$ true positive. On the other hand the families that display a number of residue pairs with high DCA score and not in contact in the domain structures are not frequents.
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