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\begin{itemize}  \item We collect all PDB with a biological assembly that contains homo-oligomers of the pfam domain selected.  \item We create a map between the alignment positions and the 3D inter-residues real positions for each PDB ( \textbf{backmapping} ) To do so we extract the real positions between residues:  \begin{itemize} \begin{enumerate}  \item within the domains on the different chains, i.e. the \textit{intra-chains distances},   \item between different chains (pairing of the domains with the homo-oligomers), i.e. the \textit{inter-chains distances}.  \end{itemize} \end{enumerate}  \item We select only chains that have a given coverage of the domain, backmapped part of the domain over ??$60%$.   \item In order to include only interacting homo-oligomers we filter out the ones that have an interaction surface under a given threshold.  \item s 
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