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\section{Conclusion}  The strongest conclusion of this argument is that, from From  the hypothesis that the universe is not created and a few basic mathematical properties one can predict, with $100\%$ certainty, that we can't know how a non-zero fraction of the observable part of our universe works, for many reasonable definitions of fraction. Either we can't apply any scientific theory to the distant past, future, or to distant places (e.g. most of astronomy would become just a joke), and we will never be able to do that, or one of the starting axioms must be false. I'm not betting on either astronomy being a joke or the mathematical statements being false. In other words, if our world is not designed, there is a good chance that we may know a lot about what happens on Earth, maybe something about what happens in our solar system, we almost surely don't know what happens in our galaxy and outside of it and we will never know a non-trivial part of what we can observe. Also, we have a good chance of knowing how the world works now and in the near past and future, but we probably don't know what were the physical laws in the distant past or how they will be in the distant future.