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Kevin J. Black edited Conclusions.md
almost 7 years ago
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# Conclusions
_To Advances in many areas of TS research and clinical care were reported in 2016. Smaller pilot studies remain important for purposes other than settling a question: they can be
completed._
## ~~Looking ahead~~ useful for feasibility, for improving methods, and for identifying new hypotheses. Several of the studies mentioned above fulfil one or more of these goals, and one of the most significant publications in TS history was a single-blind _N_-of-1 study \cite{Stevens:Blachly:1966}.
Nevertheless, as the title of the [Frontiers research topic](http://journal.frontiersin.org/researchtopic/4176/the-neurobiology-and-genetics-of-gilles-de-la-tourette-syndrome-new-avenues-through-large-scale-coll) suggests, TS research is beginning to grow from case series and small pilot studies into finding "new avenues through large-scale collaborative projects." This change is important, especially in light of increasing recognition that reproducibility is an important concern in all of science, and clearly in neuroscience \cite{23571845,27225100}. Larger samples are important to addressing this concern, and give greater hope for important new discoveries in the future.
