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{\textbf{NOTE:}}   \begin{flushleft}  \textbf{NOTE:}  This is an unreviewed preprint version of an article whose final version appears at \textit{F1000Research} \textbf{5}:1493, 2016 (doi:~\href{http://dx.doi.org/10.12688/f1000research.8428.1}{10.12688/f1000research.8428.1}). (doi: \href{http://dx.doi.org/10.12688/f1000research.8428.1}{10.12688/f1000research.8428.1}).  \end{flushleft}  Copyright \copyright\ 2015-2016, the authors