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## Phenomenology and natural history    |**Citation** | **Title** |**Section** |  **Comment** | |:------------|:----------|:------------|:------------|  | \citep{25561540} | Targeted ablation of cholinergic interneurons in the dorsolateral striatum produces behavioral manifestations of Tourette syndrome. | Pathophysiology | Discussed in \citep{Richards_2015}. | |:------------|:----------|:------------|  | \citep{Greene_2015_NTsuppress} | Reward enhances tic suppression in children within months of tic disorder onset |Phenomenology | – |  | \citep{25185800} | Visual feedback of own tics increases tic frequency in patients with Tourette’s syndrome. | Pathophysiology | – |   | \citep{Greene_striatal_fcMRI} | Multivariate pattern classification of pediatric Tourette syndrome using functional connectivity MRI | Pathophysiology | – |  | \citep{25199956} | [Transcriptome analysis of the human striatum in Tourette syndrome] | Pathophysiology |  – | | \citep{25671412} | Lifetime prevalence, age of risk, and genetic relationships of comorbid psychiatric disorders in Tourette syndrome |Etiology, Phenomenology |  This is an important, large study of psychiatric comorbidity in TS. | | \citep{25193042} | Influence of gender on Tourette syndrome beyond adolescence |Pathophysiology, Phenomenology |  Pursues a key question about TS: Why are boys at higher risk? | | \citep{25486384} | Attention and tic suppression in TS |Phenomenology | – |   | \citep{25735483} | Astrocyte metabolism in TS | Etiology, Pathophysiology |  – | | [Budman et al, in press](http://link.springer.com/article/10.1007/s40474-015-0059-1) | "Rage attacks" in TS |Phenomenology |  – |