Cheryl Richards edited Pathophysiology.md  about 8 years ago

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|  |Sensorimotor cortex and insula\citep{26538289}|More intense premonitory urges were associated with thinning in these areas.|  |  TS classification\citep{Greene:Multivariate pattern classification}|Resting state functional connectivity was used to predict group membership for individual subjects.|  |Brain structural MRI in pediatric Tourette syndrome \citep{TSANIC:VBM:London} |A large multisite study found TS children had greater gray matter volume in the posterior thalamus and hypothalamus-midbrain in addition to decreased white mater volume in the orbital prefrontal cortex and the anterior cingulate.|  |  |Tourette syndrome and chronic tic disorder \citep{26531497} |Event-related potentials recordings, during a stimulus-response compatibility task, revealed increased parietal and central activation for both patient groups compared to the control group. The two patient groups were not significantly different from one another.| 

*Title** | **Comment** |  |:----------|:------------|  | Anthropomorphic triangles \citep*{26177119} | This clever study results from Dr. Eddy's research on social cognition in TS. People with TS and controls demonstrated intact mentalizing when observing animated triangles demonstrating simple and complex interactions. However, people with TS tended to attribute human-like intentions when the two triangles were moving randomly. This tendency was not explained by other constructs such as executive function, alexithymia or clinical symptoms.|  |  | The eyes have it \citep{26175694} | A measure of cognitive control explained half of the variance in tic severity. Blink rate—related to dopamine—was higher in children with TS than in controls. Pupil diameter—related to norepinephrine—was correlated with anxiety. |