Cheryl Richards edited Treatment.md  about 8 years ago

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| **Title** | **Comment** |  |:----------|:------------|  |Is medication a tic trigger? \cite{26299294} | A meta-analysis of 22 studies involving 2,385 children found no causal relationship between stimulants and ticonset, but did demonstrate the high rate of new  onset or worsening although  tics were  associated with ADHD itself (5.7% in the psychostimulant groups and 6.5% in the placebo groups). | | [Vigabatrin RCT](http://ir.catalystpharma.com/releasedetail.cfm?ReleaseID=919254) | Four patients with treatment-refractory TS were studied in this early report of results using medication from the GABA-aminotransferase inhibitor class. One patient had a clinically significant reduction in tics while two others had tic reduction of approximately 25% but did not report subjective clinical improvement. |  ### Neurosurgery