Cheryl Richards edited Pathophysiology.md  about 8 years ago

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|  |Motor execution and motor imagery \cite{26566185}|An exploratory study found neural hyperactivation for both types of tasks when TS adults were compared to controls. Interestingly, the exception to this was that basal ganglia and thalamic activation was smaller in the TS subjects than the controls. Premotor activation during the motor imagery tasks was correlated with tic severity. |  |  |Sensorimotor cortex and insula\citep{26538289} insula \citep{26538289}  |More intense premonitory urges were associated with thinning in these areas.| |  |Brain structural MRI in pediatric Tourette syndrome \citep{TSANIC:VBM:London}|A large multisite study found TS children had greater gray matter volume in the posterior thalamus and hypothalamus-midbrain in addition to decreased white mater volume in the orbital prefrontal cortex and the anterior cingulate.|  |