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### Course  Baby videos provide a clue \cite{26246137} 34 children in Italy were identified as having autistic behaviors in their second year of life. Families reported that development during the first year of life had been normal and they donatedthe  videos that had been recorded before the age of 6 months. Videos of 18 boys were examined in detail. Abnormal general movements, which are spontaneously generated by central pattern generators and modulated by more rostral brain regions, were seen in  10 of the 11 boys who were eventually diagnosed with autism spectrum disorder between the ages of 3 and 7 years. disorder.  In contrast, normal general movements were seen in the 8 boys who had autistic features. Interestinly, features and  7 of the 8 these  boyswith transient autistic behaviors  were later diagnosed with Tourette syndrome and syndrome.  4 of the boys who were eventually diagnosed  with autism spectrum disorder were diagnosed with had  TS as a comorbidity. These results, combined with the recent nearly ubiquitous availability of home baby videos in some cultures, suggest a pseudo-prospective study design that could be used  to identify features predicting later development of TS. Clinical features associated with an early onset in chronic tic disorders \cite{26596364}. The clinical characteristics of children who developed TS before the age of 4 were compared with those who were older than 6. The younger group had a higher rate of stuttering, other speech disfluencies (e.g., speech initiation difficulties, speech prolongation), and oppositional defiant disorder. There was no difference between the two groups in rate of ADHD or obsessive-compulsive symptoms. Interestingly, the early-onset group was more likely to have a mother with tics. The authors suggested that this difference in onset age might be related to mother sensitivity to the child's symptoms resulting in tics being diagnosed at a younger age, possible prenatal or perinatal environmental factors or "maternally transmitted epigenetic modification or genomic imprinting which may be related to tic onset." An alternative explanation may come from the fact that TS is much less common in girls than in boys, so tics in a woman may represent a higher genetic load. Just as a tall woman may have taller children than an equally tall man (all other things being equal), so children of a woman with tics may be more likely to have earlier onset than children of a man with tics.