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| **Title** | **Comment** |  |:----------|:------------|  |Motor execution and motor imagery \citep{26566185}| An exploratory study found increased cortical premotor and prefrontal neural activation for both imagined and performed movements in TS subjects compared to controls. However, basal ganglia and thalamic activation was smaller in the TS subjects than the controls. Premotor activation during the motor imagery task was correlated with tic severity. |  |Brain structural MRI in pediatric Tourette syndrome \citep{TSANIC:VBM:London}| A preliminary report of a multi-site study with over 200 subjects found TS children had greater gray matter volume in the posterior thalamus, hypothalamus and midbrain in addition to decreased white mater matter  volume in the orbital prefrontal cortex. | |DTI and the corpus callosum \citep{26747579} |Axial diffusivity (AD) was reduced in treatment-naive boys with "pure TS" compared to controls. AD was negatively correlated with tic severity although this result did not reach significance after Bonferroni correction. |  ### Electrophysiology