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Cheryl Richards edited Pathophysiology.md
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| **Title** | **Comment** |
|:----------|:------------|
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Tourette syndrome Event-related potentials in TS and chronic tic disorder \citep{26531497}
|Event-related potentials recorded during a stimulus-response compatibility task revealed |Both TS and chronic tic disorder groups exhibited similar increased parietal and central activation
for both patient groups compared to the control group. The two patient groups did not differ significantly from each another, adding to the evidence that the distinction between TS and CTD may not be particularly useful.|
| Event-related topography and the effect of comorbidities \citep{Germain_2015} |
Reduced P300
amplitude amplitudes in
the frontal
region was reduced for TS patients with comorbid symptoms compared to control subjects using an Oddball paradigm. In contrast, there was no difference between a medication-naive TS group with no comorbid conditions and the control group. These results suggest that P300 differences in TS are due to working memory differences regions were related to TS-associated comorbidities rather than to TS itself. |
|
Magnetoencephalography with a Go/No-Go task \citep{26649991}. | TS adults exhibited increased beta power in the left sensorimotor, parieto-occipital and frontal areas, compared to controls, during finger preparation, and in left sensorimotor regions during the Go condition. These results are consistent with decreased BOLD activation in left motor regions for TS patients, compared to controls, on Go trials. |
### Pharmacological studies