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Baby videos were used in a study in Italy of 34 children who were exhibiting autistic behaviors in their second year of life \citep{26246137}. Families reported that development during the first year of life had been normal and they donated videos that had been recorded before these children were 6 months old. Videos of 18 boys were examined in detail. General movements, which are spontaneously generated by central pattern generators and modulated by more rostral brain regions, could be assessed only in 14 based on the videos provided. Abnormal general movements were seen in 7 of the 8 boys who were eventually diagnosed with autism spectrum disorder while the autistic behaviors in five of the six with normal general movements were transient. Although 11 of the 18 subjects were eventually diagnosed with TS, 3 of the TS subjects had inadequate baby videos for evaluating general movements. Of the remaining 8, five had exhibited normal general movements. Given that several TS subjects had comorbid ASD the abnormal movements in this subgroup might have been associated with the presence of autism. However, these results, combined with the nearly ubiquitous availability of home baby videos in some cultures, suggest that a similar pseudo-prospective study design could be used to identify behavioral features predicting later development of TS.  The clinical characteristics of children who developed TS before the age of 4 were compared with those who were older than 6 at tic onset \citep{26596364}. The younger group had a higher rate ofstuttering, other  speech dysfluencies (e.g., speech initiation difficulties, speech prolongation), stuttering)  and oppositional defiant disorder. There was no difference between the two groups in prevalence of ADHD or obsessive-compulsive symptoms. Interestingly, the children in the  early-onset group was were  more likely to have a mother mothers  with tics. The authors suggesteda number of possible explanations. These hypotheses include the idea  that this difference in onset age might mothers with tics will  be related to mother sensitivity more likely  to recognize that  the child's symptoms children have tics  resulting in tics being diagnosed at a younger age or possible when children are younger. The authors also suggest that  prenatal or perinatal environmental factors. factors may contribute to the development of tics in their children.  An alternative explanation may be related to the fact that TS is much less common in girls than in boys. Consequently, tics in a woman may represent a higher genetic load, resulting in a more severe form of tics and an earlier age of onset in her children. Researchers re-evaluated 75 TS patients previously seen at a University-based clinic, with a mean follow-up of 9 years \citep{25193042}. This study found that reported TS impairment was more likely to decrease over time in males and increase in females. In addition, women were more likely than men to have tics in adulthood in various body regions, primarily the upper extremities. This result suggests that gender continues to influence TS symptoms beyond adolescence.