deletions | additions       diff --git a/Pathophysiology.md b/Pathophysiology.md  index 975b623..b4d1bbd 100644  --- a/Pathophysiology.md  +++ b/Pathophysiology.md 
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| **Title** | **Comment** |  |:----------|:------------|  |  | \citep{25561540} |In a rodent model removing about half of the cholinergic interneurons in the dorsolateral striatum produced increased fragmented grooming behavior in response to a repeated unpredictable acoustic startle stimuli and increased repetitive sniffing in response to D-amphetamine challenge. Ablation in the dorsomedial striatum did not produce similar deficits. None of the experimental conditions produced a change in prepulse inhibition.|   |  |Astrocyte metabolism in TS \citep{25735483} | A collaborative genetic study demonstrated an association of TS with 33 genes related to glycolysis or glutamine metabolism. None of the individual genes would have survived correction for multiple testing and the results were consistent with a combined effect of many genetic variants of small effect. These results narrow the hunt for genes that may contribute to the development of TS and they also suggest a new direction for future electrophysiological, imaging and pharmacological studies. |