deletions | additions       diff --git a/Treatment.md b/Treatment.md  index 2a26189..18776a1 100644  --- a/Treatment.md  +++ b/Treatment.md 
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\citet{25988365} dug into the data from 2 previously reported, pivotal, randomized controlled studies of behavior therapy for tics (CBIT) that together enrolled over 200 children and adults to address the question of which tics best predict treatment response to CBIT. Looking at specific tics across all subjects, the superior treatment benefit from CBIT compared to a control therapy could be attributed to differential improvement in only a few types of tics, including throat clearing and complex tics. However, tics that actually bothered people, most of which involved a premonitory urge, were more likely to respond preferentially to CBIT than to the control therapy. This result is not unexpected, since CBIT focuses first on bothersome tics, and preferably those preceded by a premonitory urge. This report also extends previous information about premonitory phenomena; about 40-60% of patients with any specific tic reported a premonitory urge for that tic.  "Living with Tics" is a modularized cognitive-behavioral treatment focused on tic-related impairment and quality of life (as opposed to focusing on tic severity and frequency _per se_), recently tested in a random allocation, waitlist control study \citep{25500348}. The active intervention included up to 10 weekly sessions for children and adolescents. Treatment modules focused on a variety of themes including topics such as self-esteem, emotion regulation, parent training, cognitive restructuring, coping at school, habit reversal training (limited to 1 or 2 sessions except for one subject who received 3 sessions) and overcoming tic-related avoidance. Those in the active treatment group had improved self-rated quality of life and reduced (blinded) clinician-rated impairment of social, family or school/work function compared to the waitlist control group. An additional 7 youth from the waitlist group then completed the treatment condition resulting in data on 19 participants for open-trial analyses. With the larger sample size the reduction in obsessive-compulsive symptoms and tic severity (i.e., 30%) was sginficant. significant.  Both the youth and their parents reported satisfaction with the intervention. Th intervention which is a reminder that improving quality of life can be a desired treatment goal.  A small uncontrolled open trial of mindfulness-based stress reduction was provided to 18 individuals who were at least 16 years old \citep{25149879}. Treatment consisted of 8 weekly 2-hour group classes and one four hour retreat. Participants were encouraged taught a tic-specific meditation exercise that involved noticing any urges to tic while maintaining a focus on one's breathing rather than trying to change or eliminate the urge to tic. Only one subject dropped out. Mean tic severity decreased by 20% and 10 subjects were rated as "much improved" or "very much improved" and thus considered treatment responders and these gains were maintained at a one month follow-up.