Cheryl Richards edited Pathophysiology.md  about 8 years ago

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### Clinical and neuropsychological studies  Baby videos provide a clue \citep{26246137} | 34 children in Italy were identified as having autistic behaviors in their second year of life. Families reported that development during the first year of life had been normal and they donated the videos that had been recorded before the age of 6 months. Videos of 18 boys were examined in detail. Abnormal general movements, which are spontaneously generated central pattern generators and modulated by more rostral brain regions, were seen 10 of the 11 boys who were eventually diagnosed with autism spectrum disorder between the ages of 3 and 7 years. In contrast, normal general movements were seen in the 8 boys who had autistic features. Interestinly, Interestingly,  7 of the 8 boys with transient autistic behaviors were later diagnosed with Tourette syndrome and 4 of the boys with autism spectrum disorder were diagnosed with TS as a comorbidity. These results, combined with the recent nearly ubiquitous availability of home baby videos in some cultures, suggest a pseudo-prospective study design to identify features predicting later development of TS. | **Title** | **Comment** |  |:----------|:------------|