A. Benjamin Chong edited In_light_of_these_events__.tex  almost 9 years ago

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In light of these events, questions remain regarding the use of clinical trials registries by systematic reviewers, and results from the few available studies addressing this issue show limited use of registries in these searches. For example, Sinnett found that only five of 78 systematic reviews in clinical neurology searched clinical trials registries \cite{Sinnett_2015}. Eight of 41 systematic reviews in emergency medicine reported searching registries\cite{Keil_2014}. registries \cite{Keil_2014}.  Even among high impact general medical journals, only 41 of 117 reviews used registry searches \cite{Jones_2014}. With recent findings suggesting significant publication bias in the reproductive health literature, we examined the use of clinical trials registries in systematic review searches in obstetrics and gynecology research. Of those systematic reviews making use of trials registries, we also investigated whether potential relevant unpublished trials were located from these searches and whether data from these unpublished trials were included in the systematic review.