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Our search of PubMed yielded 292 articles, which was narrowed to 256 articles after exclusions (Fig. 1). As displayed in Fig. 2, we examined the frequency of the use of clinical trials registries for systematic review search processes. Of the 256 articles, 47 (18.36\%) conducted a search in at least one clinical trials registry. The registries that were searched were clinicaltrials.gov (n = 44), the Chinese Clinical Trials Register (ChiCTR; n = 1), the International Clinical Trials Registry (n = 1), and the WHO Clinical Trials Registry (n = 1). Five of the articles that searched clinicaltrials.gov also searched the Australian New Zealand Clinical Trials Registry (ANZCTR). For the two articles that searched the International Clinical Trials Registry and the WHO Clinical Trials Registry, we determined that these articles are referring to the WHO ICTRP.  Fig. 1 2  also highlights that Obstetrics and Gynecology was the only publication where more than 50\% of the studies searched clinical trials registries. In the other five publications that were analyzed, the average percentage of studies that included a search of clinical trials registries was 12\%.   Of the 47 studies that searched clinical trials registries, 36 did not make a clear indication whether or not they obtained or used any data from the clinical trials registries. The other 11 systematic reviews obtained data from studies found on clinicaltrials.gov.   
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