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\subsection*{Case tree plots}  Case tree plots depict the emergence and growth of  clusters of disease over time. Placement along the x-axis corresponds with the date of illness onset for the case. When the onset date is not known, diagnosis date may be used instead. The y-axis value represents the Each  case generation. is represented by a colored node.  Nodesat generation 1 are human cases acquired from an animal source. If  that infected human passes the disease to two other humans, those two subsequent cases share an epidemiological link  areplotted at generation 2, and  connected to by an edge. The meaning of  the node color  of origin the node varies based on the node attribute chosen  by edges. Cases that do not belong the plot creator. In many cases, color simply signifies membership  to a cluster are represented as independent nodes on human to human cluster. However, it could also represent health status (e.g. alive, dead),  the plot. sex of the patient, or any other categorical attribute.  The meaning of Node placement along  the color x-axis corresponds with the date  of illness onset for  the node varies based on case. When  the node attribute. In many cases, color simply signifies membership to a onset date is not known, diagnosis date may be used instead. The y-axis value represents the case generation. Nodes at generation 1 are  human to cases acquired from an animal source. If that infected  human cluster. However, it could also represent health status (e.g. alive, dead), the sex of passes  the patient, or any disease to two  other categorical attribute. humans, those two subsequent cases are plotted at generation 2. Cases that do not belong to a cluster are not represented on the plot.  To generate a case tree plot, users provide a line listing with, at minimum: unique case identifiers, the date of illness onset (or the date the illness was reported, if onset date is not available), and cluster membership, as seen in table~\ref{tab:linelist}. Any additional relevant variables like patient age and sex may also be included.