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\section*{Materials and methods}   Please provide a detailed account of the methods and materials used for the study in order to allow replication by other researchers.   If you have used a standard protocol that is published elsewhere (e.g. Nature Protocols, Current Protocols), a reference may be used. Please include Things case tree plots are good at  \begin{itemize} \item the source of all samples, reagents, antibodies etc. estimating spillover frequency  \item how samples were selectedwhat exclusions were made, if any; estimating $R0$ (human to human transmissibility)  \item what was being measured identifying superspreaders  \item for processed data, any software used to process the data and, where possible, the source code should be made openly available.\item     for laboratory animal studies, we recommend compliance with the \href{http://www.nc3rs.org.uk/downloaddoc.asp?id=1206&page=1357&skin=0}{`Animal Research: Reporting In Vivo Experiments' (ARRIVE) guidelines}, developed analyzing case outcomes  by NC3Rs to improve standards of reporting to ensure that the data from animal experiments can be fully scrutinized generation  and utilized.\item     allowances made, if any, for controlling bias or unwanted sources of variability.   Limitations of the datasets.\item     acronyms and abbreviations must be explained by cluster  \end{itemize}