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Caitlin Rivers edited results.tex
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\section*{Results}
Case tree plots are produced using the epipy package for Python. All code is available on github.
The x-axis represents time, and the y axis represents generation. Nodes at generation 1 are
human cases
acquired from
a zoonotic an animal source. If that
infected human
were to pass passes the disease to two other humans, those two subsequent cases are
both plotted at generation
2. 2, and connected to the node of origin by edges. Cases that do not belong to a cluster are represented as independent nodes on the plot. The meaning of the color of the node varies based on the node attribute. In many cases, color simply signifies membership to a human to human cluster. However, it could also represent health status (e.g. alive, dead), the sex of the patient, or any other categorical attribute.
The meaning of the color of the node varies based on the node attribute. In many cases, color just signifies membership to a human to human cluster. However, it could also represent health status (e.g. alive, dead), the sex of the patient, etc. To generate a case tree plot, users provide a line listing with, at minimum: case ids, date of illness onset, and cluster
membership. An example can be membership, as seen in table~\ref{tab:linelist}. Any additional variables like patient age and sex may also be
included, as can cases not belonging to a cluster, though they will not be represented in the plot. included.
\begin{table}
\centering
...
\label{tab:linelist}
\end{table}
Users must also provide the mean and standard deviation of the generation time between cases. The line listing need not specify the chain of transmission;
epipy the case tree plot generator will estimate the chain
of transmission based on the onset dates based
on these values. The earliest case in an outbreak is assumed to be of zoonotic origin, and will be plotted as generation
1. Cases within one standard deviation of generation 1 will be identified as generation 2. time values. Cases
belonging to the same cluster that have an onset date within one standard deviation of
the mean generation
2 will time are assumed to be
plotted as generation 3, and so on. linked.