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Alun Hughes edited textbf_C15_iFR_has_been__.tex
almost 9 years ago
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\textbf{[C15].} iFR has been proposed as a clinical measurement in stenosed coronary arteries and there has never been any suggestion that it be applied anywhere other than the coronary system. It should be clear by now that iFR is not a measure of minimal (vasodilated) coronary resistance, but repetition of the fallacy requires repetition of the correction.
\textbf{[C16].} As already pointed out, iFR is exactly the same ratio as FFR, but calculated during the wave-free period in diastole rather than after administration of
Adenosine. adenosine. In the first paper on iFR, the correlation between iFR and FFR measured in a small cohort of patients was measured and found to be very high. In subsequent papers and in the ongoing clinical trials it is the clinical efficacy of iFR that is compared to the clinical efficacy of FFR, not the quantities themselves that are compared. We believe that this is a important distinction.