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In direct comparison of methylation for an individual oyster prior to and following heat shock approximately 10k differentially methylated features were identified as defined by >/= 1.8 difference. For all oysters a majority of the features (probe region) were hypomethylated. Specifically, for oysters #2, #4, and #6 the number of hypomethylated features was 7224, 6560, and 7645, respectively. Genome feature tracks (bedGraph) for each oysters are available: genome-feature-tracks/2014.07.02.2M_sig.bedGraph, genome-feature-tracks/2014.07.02.4M_sig.bedGraph, genome-feature-tracks/2014.07.02.6M_sig.bedGraph.       Figure - Screenshot of genome feature tracks showing differential methylation.  When only features were considered where at least 3 adjacent probes were also differentially methylated the number of features (adjacent probes merged) for oysters #2, #4, and #6 was 112, 58, and 62, respectively. A majority of these features were hypomethylated (108, 48, and 53, respectively) 
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In order to examine regions that were differentially methylated across all three oysters, features were identified where there were at least 3 adjacent probes with significantly differentially methylated. A total of 111 features were identified as hypomethylated and 54 features as hypermethylated when differentially methylated probe with 100bp were merged.