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Antonio Prestes García edited figures/paper-20(LinearGraph-0)v2/caption.tex
over 8 years ago
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Replace this text Hence assuming the functional similarity between conjugation and networks a common metrics can be used to analyze the process. One of these metrics is the total delay required for flooding all nodes in the network with
your caption some message $\mathcal{M}$ which in the bacterial context is given by the Equation ~\eqref{eq:delay}
\
\begin{equation}
\label{eq:delay}
\tau = N \times T + (H - 1) \times P + (H - 1) \times T
\end{equation}
\
being N the number of messages being forwarded, T the time required for transmitting the message, P the time needed for each node to process the message before being able to forward it again and finally H stands for the number of hops in or network. Putting it in terms of bacterial conjugation we have that N represents the plasmid size in kilobases, T the time required to move a single kilobase from a cell to another, P may represent the two sources of delay which are referred as recovery and maturation time for donors and recipient cells respectively. Finally H is the actual number of bacterial cells in the linear topology already mentioned.
The aggregated value referred globally as maturation time includes, amongst other factors, (a) the time required for adding the second strand to the plasmid inside the new formed transconjugant cells, (b) the time required to express all genes coding the proteins for the trans-envelope apparatus, and (c) possibly the effect of SOS response triggered by entrance of single stranded DNA into the transconjugant cell\cite{citeulike:8298094}.
