Lucas de Levy Oliveira edited section_Methods_subsection_Pre_processing__.tex  almost 9 years ago

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Other preprocessing methods can be used at this point, such as Common Average Reference (CAR) method. This tool averages all electrode inputs and removes the value calculated from all other signals in order to decrease noise contribution.  \subsection{Spike detection and frequency measurement}  There are several ways of implementing a spike detection algorithm. One could use Wavelet Transform or feature extraction methods, but none seemed to be more popular and simple than voltage threshold. Simply put, the method sets a  threshold detection. above which the voltage of the neuron is considered a spike. Afterwards, it must wait for a specific time (depending on the action potential period) to being looking for spikes again. Once spikes are detected properly, a dynamic time window can be used to determine spike rate but a mere division of "quantity of spikes detected" by "time frame".  Also, tools such as Peristimulus Time Histogram (PSTH) can be used at this point in order to study variations of frequency rate, as done in \cite{22170970}.